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. Author manuscript; available in PMC: 2008 May 5.
Published in final edited form as: Toxicol Sci. 2006 Mar 28;91(2):620–630. doi: 10.1093/toxsci/kfj170

TABLE 5.

Organs Examined Histopathologically

Adrenals Aorta (thoracic) Brain
Cecum Cervixa Colon
Duodenum Epididymes Esophagus
Eyes Femur Gallbladder
Gonads Harderian glandsb Heart
Injection sites (including underlying muscle and overlying subcutis) Ileum Jejunum
Kidneysc Lacrimal glands Liver
Lung with main stem bronchii Mandibular or submandibular lymph nodes Mandibular salivary glands
Mesenteric lymph nodes Mammary glands (♀, ♂) Optic nervesd
Pancreas Parathyroids Pituitary
Prostate Rectum Seminal vesicles
Sciatic nerve Skeletal muscled Skin
Spinal cord (cervical, midthoracic, lumbar) Spleen Sternume
Stomach Thymus Thyroids
Trachea Tongue Urinary bladder
Uterus Vagina Gross lesions
Animal IDf
a

In studies I, III, V, VI, and VII, not analyzed in studies II and IV.

b

In all studies except study II.

c

Left kidney snap-frozen for analysis of immunotoxicity if indicated, in studies V, VI, and VII.

d

Not analyzed in studies I, II, III, and IV.

e

Includes bone with marrow.

f

Not analyzed in studies II, III, and IV.