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. Author manuscript; available in PMC: 2008 May 5.
Published in final edited form as: Clin Cancer Res. 2005 Jun 15;11(12):4495–4503. doi: 10.1158/1078-0432.CCR-04-2363

Fig. 3.

Fig. 3

IE1-pp65 ^ transfected autologous CD40-B cells expand CD4 and CD8 responses to the fusion protein and CD8 responses to pp65[495−503] peptide. CD3 Tcells from three CMV-seropositive/HLA-A*0201 ^ positive individuals (D1, D3,and D8) were stimulated weekly 3with IE1-pp65 fusion gene ^ transfected autologous CD40-B

× cells. Pre, at start of culture; post, after expansion in cultureT-cell responses were measured by IFN-γ ICC assay. Absolute numbers of responding CD4 and CD8 Tcells are shown before and after stimulation. All individuals showed 2 to 3 log-fold increases in target-specific CD4 and CD8 Tcells.