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. Author manuscript; available in PMC: 2008 May 5.
Published in final edited form as: Clin Cancer Res. 2005 Jun 15;11(12):4495–4503. doi: 10.1158/1078-0432.CCR-04-2363

Fig. 5.

Fig. 5

Repeated stimulations with PGP-transfected CD40B cells induces a T-cell response with specificity for CML cells. CD3+ T cells obtained from PBMC of patient 5 with CML at day 100 post–bone marrow transplantation were stimulated weekly with PGP-transfected CD40B cells from the HLA-identical sibling donor, and tested for cytotoxicity against autologous CML cells and against normal bone marrow cells from the donor after the fourth stimulation (week 4). The PR3, HNE, and cathepsin-G–induced Tcell lines selectively recognized CML cells but not normal cells. E:Tratio, effector-to-target ratio.