Table 3.
Stimulators | CD4 (%) | CD8 (%) | CD4+/IFN-γ+ (%) | CD8+/IFN-γ+ (%) |
---|---|---|---|---|
Untransfected | ||||
None | 54 | 46 | — | — |
CD40B | 72 | 28 | 0.59 | 0.13 |
CD40B+ PR1 | 77 | 23 | 0.1 | 0.19 |
Transfected | ||||
Mock | 67 | 33 | 0.12 | 0.16 |
PR3 | 55 | 45 | 1.07 | 0.47 |
HNE | 75 | 25 | 0.72 | 1.34 |
Cathepsin-G | 70 | 30 | 0.87 | 0.51 |
NOTE: Only PGP-transfected CD40B cells elicited significant increases in IFN-γ upon stimulation with autologous leukemic blasts. Significant differences are in bold.