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. Author manuscript; available in PMC: 2008 May 5.
Published in final edited form as: Mamm Genome. 2007 Mar 8;18(2):87–93. doi: 10.1007/s00335-006-0090-y

Table 1.

Genotype probabilities, genotype means, and variance attributable to a segregating locus as a function of genetic model and cross type

Probability
Genotype Mean F2 BCA BCB RIL
AA μ + αδ/2 ¼ ½ 0 ½
AB μ + δ/2 ½ ½ ½ 0
BB μ − α −δ/2 ¼ 0 ½ ½
Variance attributable to locus
Model Parameter F2 BCA BCB RIL

General ¼ δ2+ ½ α2 ¼ (α + δ)2 ¼ (α + δ)2 α2
No dominance δ = 0 ½ α2 ¼ α2 ¼ α2 α2
A dominant δ = α 3/2 α2 0 α2 α2
B dominant δ = −α 3/2 α2 α2 0 α2
No additive α = 0 ¼ δ2 ¼ δ2 ¼ δ2 0

F2 = intercross; BCA = backcross to the A strain; BCB = backcross to the B strain; and RIL = recombinant inbred lines.