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. Author manuscript; available in PMC: 2008 May 5.
Published in final edited form as: Ann N Y Acad Sci. 2008 Mar;1123:105–112. doi: 10.1196/annals.1420.012

TABLE 2.

Effectiveness of ranolazine, lidocaine, propafenone, and chronic amiodarone in terminating and preventing induction of acetylcholine-mediated AF in coronary artery–perfused right atrial preparations

Ranolazine (10.0 μM) Lidocaine (21.0 μM) Propafenone (1.5–3.0 μM) Chronic Amiodarone
Termination of AF 66% (4/6) 33% (2/6) 100% (7/7) NA
Prevention of induction of AF 80% (8/10) 57% (4/7) 100% (6/6) 83% (5/6)

Note: Persistent AF was inducible in 100% of atria under baseline conditions. (Modified from Burashnikov et al.2,3)