. Author manuscript; available in PMC: 2008 May 5.

Published in final edited form as: J Affect Disord. 2007 Jan 23;101(1-3):195–200. doi: 10.1016/j.jad.2006.11.020

Table 2.

Different response cutoffs on the modified 17-item Hamilton Depression Rating Scale

Cutoff	N	BL H17	BL H24	BL HDRS17Mod	SD HDRS17Mod	(BL-SD) HDRS17Mod	% Drop HDRS17Mod
30%
Responders	12	19.9±2.8	26.5±4.1	15.2±2.4	7.7±2.4^*	7.5±3.0^*	47.5±11.2^*
Nonresponders	11	19.6±3.1	25.4±4.5	15.9±3.4	13.0±3.6	2.9±3.1	13.7±17.2
35%
Responders	11	20.1±2.9	26.7±4.2	15.5±2.2	7.9±2.4^*	7.6±3.1^*	48.8±10.7^*
Nonresponders	12	19.4±3.0	25.3±4.4	15.5±3.6	12.3±4.2	3.2±3.1	15.3±17.3
40%
Responders	8	20.5±3.2	27.3±4.7	16.3±2.0	7.3±2.4^*	9.0±2.3^*	53.3±8.9^*
Nonresponders	15	19.3±2.8	25.3±3.9	15.1±3.3	11.8±3.9	3.3±2.8	19.6±17.7
50%
Responders	5	20.6±3.8	27.2±5.9	15.8±2.2	5.8±1.6^*	10.0±1.4^*	57.8±8.4^*
Nonresponders	18	19.5±2.7	25.6±3.8	15.4±3.1	11.4±3.6	4.0±3.1	24.0±19.0

BL: Baseline;

H17: 17-item Hamilton Depression Rating Scale;

H24: 24-item Hamilton Depression Rating Scale;

HDRS17Mod: Modified 17-item Hamilton Depression Rating Scale (omitting sleep and weight loss items);

SD: Sleep deprived.

Mean±standard deviation.

% Drop HDRS17Mod was used to dichotomize responders vs. nonresponders.

P<0.01, t-test, one-tailed, df=21.