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. Author manuscript; available in PMC: 2008 Jun 1.
Published in final edited form as: Gastroenterology. 2007 Apr 13;132(7):2422–2437. doi: 10.1053/j.gastro.2007.03.101

Figure 5.

Figure 5

Effect of pretreatment with tryptase and trypsin inhibitors on TxA-induced enteritis. Mice were preinjected with FUT-175, MPI-0442352, or SBTI before injection with vehicle (vehicle control, open bars) or 1.0 μg TxA (closed bars). (A) Intestinal secretion expressed as milligram per centimeter of loop. (B) Tissue MPO expressed as units per milligram protein. (C) MPO in loop fluid expressed as units per milliliter of fluid. (D) Structure of MPI-0442352. *P < .05 between vehicle control and TxA loops in vehicle-pretreated mice. †P < .05 between results obtained with TxA in mice pretreated with vehicle compared with protease inhibitors.