Table 1.

Histologic Score for TxA-Induced Enteritis in Par₂^+/+, Par₂⁺/⁻, and Par₂>^−/− Mice

Mice genotype and treatment	Epithelial damage	Edema congestion	Polymorphonuclear leukocyte infiltration	Total score
Par2+/+ + vehicle control	0.16 ± 0.1	0.50 ± 0.1	0.68 ± 0.3	1.34 ± 0.4
Par2+/+ + TxA	0.91 ± 0.1a	1.35 ± 0.1a	2.21 ± 0.1a	4.47 ± 0.3a
Par2+/− + vehicle control	0.06 ± 0.1	0.25 ± 0.1	0.81 ± 0.1	1.13 ± 0.2
Par2+/− + TxA	0.89 ± 0.2	1.00 ± 0.1	1.73 ± 0.2b	3.61 ± 0.4
Par2−/− + vehicle control	0.35 ± 0.2	0.45 ± 0.2	0.75 ± 0.1	1.55 ± 0.5
Par2−/− + TxA	0.25 ± 0.1b	0.75 ± 0.2b	1.70 ± 0.2b	2.70 ± 0.3b

^aP < .05 compared with Par₂^+/+ vehicle control group.

^bP < .05 compared with Par₂^+/+ TxA group.