Table 1.

Residues contacting inducer IPTG in crystal structure 1LBH^a or 1TLF^b

Residue	Nature of Contacta	Changes in TMD
S69	SC Hydrogen bond	N
L73	Hydrophobic	Y
A75	Hydrophobic	N
P76	Hydrophobic	N
I79	Hydrophobic	N
R101	SC Hydrogen bond	N
D149	SC Hydrogen bond	Y
R197	SC Hydrogen bond	Y
W220	Hydrophobic/vdW	N
N246	SC Hydrogen bond	Y
D274	SC Hydrogen bond	Y
F293	Hydrophobic	Y
L296	Hydrophobic	Y

^aLewis et al. 1996;

^bFriedman et al. 1995;