Figure 2.

Sequence alignment of the Sac10b family. Mja10b, Methanococcus jannaschii (Q57665); Ssh10b, Sulfolobu shibatae; Sso10b, S. solfataricus (P74761); Pho10b, Pyrococcus horikoshi (O74101); Pab10b, P. abyssi (Q9VIN3); Afu10b1, Afu10b2, Archaeoglobus fulgidus (O28323,O29195); Tac10b, Thermoplasma acidophilum (Q9HJQ5); Tvo10b, T. Volcanium (Q97955); Mth10b, Methanobacterium thermoautotrophicum (O27527); Ape10b1, Ape10b2, Aeropyrum pernix (Q9YAX2, Q9YAW1). The secondary structure of Mja10b derived from the crystal structure is shown above the alignment. The residues in the conserved motif are marked with an “*.” Residues involved in hydrophobic interactions between the two monomers at the dimer interface are marked with a “+.”