Fig. 1. Multi-way sensitivity analysis examining scenario when two regimens of antiretroviral therapy are available.
Lines represent the different costs of a boosted protease inhibitor (PI) regimen with the base case indicated by the lower right line and 80% base case costs with the upper left line. The region to the left of the applicable cost line represents the scenarios for which it is preferable to start with a non-nucleoside reverse transcriptase inhibitor (NNRTI)-based therapy, followed by a PI-based therapy upon immunological failure (NNRTI to PI). The region to the right of the applicable cost line represents the scenarios for which it is preferable to start with a PI-based therapy, followed by an NNRTI-based therapy (PI to NNRTI). The base case scenario is indicated by the line with the open circles. The horizontal dotted line represents the base case boosted PI-based regimen efficacy when used as second line.
