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. Author manuscript; available in PMC: 2008 May 5.
Published in final edited form as: J Neurovirol. 2007 Aug;13(4):373–383. doi: 10.1080/13550280701344983

Figure 6.

Figure 6

Mice lacking the STAT1 gene suffer accelerated mortality and increased viral brain titers. Newborn STAT1 gene-deficient mouse pups (dashed lines) and syngeneic controls (129SvEv) (solid lines) were transferred to Swiss Webster surrogate mothers and T3A (black) or T1L (gray) infected at 2 days of age with 1 × 102 PFU of virus (i.c.). Survival was assessed in these animals with twice daily monitoring up to 21 days post infection (A). Viral brain titers were assessed following the same viral infection paradigm in T3A- (B) and T1L- (C) infected wild-type (open columns) and STAT1 gene-deficient (closed columns) animals at 7 days post infection. Vertical bars indicate SEM from a minimum of five observations. *P < .05.