Table 2.

Distribution of mutations leading to Rif^r in B. anthracis rpoB gene

B. anthracis site (bp)	Amino acid change	Base-pair change	Spontaneousa	dnaN1	mutSb
1403	Q454R	AT→GC	20	13	19
1442	H467R	AT→GC	30	30	20
1441	H467Y	GC→AT	33	2	1
1391	S450F	GC→AT	0	0	0
1457	S472F	GC→AT	1	0	0
1457	S472Y	GC→TA	1	0	0
1402	Q454K	GC→TA	4	1	0
1403	Q454L	AT→TA	0	0	0
1417	T459S	AT→TA	0	0	0
1444	K468Q	AT→CG	0	0	0
1442	H467P	AT→CG	1	0	0
1391	S450C	GC→CG	0	0	0
1441	H467D	GC→CG	0	1	0
1600	S453C	GC→CG	0	0	0
Total 14			90	47	40

^aIncludes data from ref. 31.

^bFrom ref. 31.