Table 1.

 Serum response (as fold difference) in terms of hemagglutination inhibition (HAI) and to native and denatured red cell‐bound virus after vaccination, compared with the corresponding pre‐vaccination sample

Subject	Dose (μg)	Fold HAI (log2)* Panama/99	Native			Denatured
			Pre‐vac A 405	Fold A max Panama/99	Fold K a Panama/99	Pre‐vac A 405	Fold Amax Panama/99	Fold K a Panama/99
D	Placebo	1	0.8	1.0	0.9	0.6	1.1	0.8
H	Placebo	1	0.4	0.9	1.1	0.4	1.0	0.8
L	Placebo	1	0.7	1.1	1.4	0.5	1.0	0.8
P	Placebo	1.8	0.4	1.0	0.9	0.3	0.8	1.1
T	Placebo	1	0.7	1.1	1.2	0.5	1.1	1.1
W	Placebo	1	0.4	1.0	0.8	0.4	1.1	1.2
A	15	1	0.8	1.0	1.2	0.8	1.2	1.0
E	15	1.3	0.9	1.2	1.9	0.7	1.2	2.1
I	15	1.3	0.7	1.1	1.1	0.7	1.1	1.1
M	15	1.5	0.4	1.5	0.6	0.3	2.0	0.5
Q	15	1	0.7	1.1	0.7	0.4	1.0	0.9
U	15	1.5	0.5	1.1	1.2	0.5	0.8	2.5
X	15	1	0.4	1.1	1.4	0.3	1.2	1.4
AA	15	2	0.9	1.2	2.2	0.9	1.2	2.3
DD	15	3.5	0.2	3.6	1.4	0.1	2.2	5.0
GG	15	1.3	0.4	1.4	2.6	0.3	1.8	2.5
B	30	1	0.4	1.1	1.0	0.3	1.4	0.9
F	30	1	0.3	2.3	0.4	0.1	1.7	0.9
J	30	1	0.4	1.2	1.0	0.2	1.8	0.7
N	30	1.5	0.6	1.2	1.5	0.6	0.8	1.9
R	30	1	0.7	1.0	2.1	0.6	0.9	3.6
Y	30	1	1.0	0.8	2.2	0.7	1.1	1.2
BB	30	1.4	0.6	1.1	1.3	0.5	1.1	1.5
EE	30	2.3	0.3	1.6	5.2	0.1	1.6	5.0
HH	30	1.6	0.2	1.6	3.4	0.1	2.7	3.2
II	30	2.3	0.3	1.5	1.1	0.2	1.4	2.2
C	60	0.9	0.8	1.0	1.1	0.5	1.4	0.8
G	60	1	0.5	1.3	2.0	0.3	1.0	2.7
K	60	1	0.4	1.1	1.4	0.4	1.0	1.5
O	60	1.3	0.6	1.0	2.4	0.6	0.9	2.8
S	60	2	0.5	1.5	3.2	0.5	1.2	3.9
V	60	1.3	0.6	1.3	2.9	0.4	1.0	4.0
Z	60	1.4	0.7	0.9	1.1	0.5	1.0	1.6
CC	60	1	0.9	0.9	0.9	0.8	1.0	1.3
FF	60	3	0.2	5.1	0.5	0.1	5.0	2.3
JJ	60	3	0.2	4.3	1.4	0.0	5.0	2.4

*The HAI responses in this vaccine trial ²⁰ and HAI for a younger population ²³ were reported earlier.