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(a) Superposition of trimeric bvPNP complexed with acyclic nucleoside phosphonate inhibitor (2,6-diamino-(S)-9-[2-(phosphonomethoxy)propyl]purine) (pdb code 1LVU, blue) and the modeled trimer of hPNP complexed with ImmH·
(pdb code 1RR6, orange). (b) Superposition of the crystal structure of monomeric bvPNP (ribbon enzyme blue; stick ImmH·
cyan) with hPNP (ribbon enzyme orange; stick ImmH·
red).
