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Diagram showing routes of water flow across GLUT2 or SGLT and the oocyte membrane. Two routes are shown. One is via the transporter through which water and cotransported solutes pass via the external tight opening, then the vestibule, then via the wide vestibular exit into the external cytosolic layer. The other route permits only water flow determined by the osmotic pressure difference between the outer cytosol and the external solution.
