TABLE 2.
Parameter | D34 cm2 s−1 | D23 cm2 s−1 | Pw13 cm s−1 | SGLT Pw12 cm s−1 | SGLT Pw12 (phloridzin) cm s−1 | SGLT Vm pmol cm−2 s−1 |
---|---|---|---|---|---|---|
Condition | 2.18 × 10−5 | 2.03 × 10−6 | 2.12 × 10−5 | 2.89 × 10−5 | 4.75 × 10−7 | 66.5 |
Parameter ratio GLUT2/SGLT1 | 1.08 | 2.05 | 0.37 | 2.05 | 80 | 341 |
Sensitivity 1 mM 3-OMG phase 1 | 0.215 | 0.231 | 0.109 | 0.080 | 0.400 | 0.096 |
Urea 20 mM phase 2 | 0.006 | 0.005 | 0.089 | 0.652 | 0.000 | 0.393 |
Inflow 3-OMG phase 3 | 0.000 | −0.048 | 0.655 | 0.293 | 0.000 | −0.288 |
Phloridzin phase 4 | 0.014 | 0.211 | 0.327 | 0.356 | 0.000 | 0.114 |
Urea 20 mM phase 5 | −0.004 | −0.139 | 1.136 | 0.141 | 0.024 | −0.045 |