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Mean (+ SE) percentage of peripheral-blood mononuclear cell–expressing marker before treatment (day 1) and on day 8 for (A) patients completing course 1 and (B) patients completing courses 1 and 2 at the same dose level. Significant differences are shown for (A) day 1 versus day 8 and (B) for course 2 versus course 1. (*), P < .05; (**), P < .01.
