Table 5.

Laboratory Changes^* Observed With EMD 273063

^*Adverse events graded 1 to 4 as per National Cancer Institute Common Toxicity Criteria, version 2.0, except as indicated.

^†Total number of patients treated at each dose level.

^‡Total number of courses administered for all patients at the indicated dose level.

^§For each category of laboratory toxicity, each patient was scored based on their highest grade of toxicity for either course of treatment.

^||The number of patients showing each grade of toxicity as their highest grade is shown for each dose level of EMD 273063.