Table 6.
Characteristic Course of Hypophosphatemia*
| Day
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 22 | 26 | |
| Serum PO4, mg/dL | 3.2 | 2.9 | 2.1 | 1.3 | 1.5 | 2.4 | 2.6 | 3.1 | 3.4 | |
| Serum creatinine, mg/dL | 1.2 | 1.3 | 1.3 | 1.1 | 1.2 | 1.2 | ||||
| Serum Na+, mg/dL | 142 | 139 | 137 | 143 | 138 | 141 | 140 | 140 | ||
| Serum K+, mg/dL | 4.4 | 4.0 | 4.0 | 4.5 | 3.7 | 4.3 | 4.5 | 4.4 | ||
| Venous blood pH | 7.39 | 7.38 | 7.43 | 7.40 | ||||||
| Urine PO4, g/24 h | 0.2 | 0.0 | 0.1 | 0.7 | 0.6 | |||||
*
A typical course of hypophosphatemia (grade 3) is demonstrated in a patient receiving EMD 273063 (6 mg/m2/d). Data shown are from course 1: hu14.18-IL2 was given on days 1, 2, and 3.