Figure 2.

PPAR-γ expression in culture rat oligodendrocytes and in white matter (postnatal day 19) in rat model of global perinatal asphyxia. (a) Immunocytochemistry of rat OL progenitor cultures, prepared as previously described [40] for PPAR-γ (upper panel) and the OL marker O4 (lower panel). (b) Western blot analysis of white matter homogenates from rats at postnatal day 19 subjected to 20 minutes of perinatal asphyxia (hypoxic) and from controls, prepared as described in Piscopo et al. [48]. Inset show the decreased levels of MBP in hypoxic rats at pnd 19.