Table 2. Loss of HOXA13 function causes increased sinusoidal and lymphatic endothelial gene expression.
Affymetrix Array Probe ID | Gene | Molecular Function/Biological Process | Fold Change MUT/WT (FDR) |
Whole Placenta Microarray | |||
1429379_at | Lyve-1/Xlkd1 | Hyaluronate receptor: maintenance of hyaluronan status in lymphatic and sinusoidal endothelia [101] | 3.60 (0.00) |
1423062_at | Igfbp3 | Igf Binding protein: maintenance of sinusoidal endothelial phenotype [57] | 1.86 (0.00) |
1450699_at | Selenbp1 | Selenium binding protein: maintenance of selenium status and sinusoidal endothelial phenotype [53] | 1.52 (0.00) |
1427457_a_at | Bmp1 | Metalloprotease: cleaves prolactin to inhibit angiogenesis [54] | 1.36 (0.00) |
1426314_at | Ednrb | Endothelin receptor: promotes sinusoidal endothelial function [56] | 1.19 (0.01) |