Table 3.
Marked changes in linkage when age was included as a covariate
| SNPa | Trait | LOD scores | ||||
| Rs no. | Location Chr:Mb | Gene | Location Chr:Mb | Without age | With age | Change when age included |
| rs1505695 | 02:06.9 | ITGB1BP1 | 02:09.5 | 3.36 | 9.82 | 6.47 |
| rs756019 | 15:21.2 | CREM | 10:35.5 | 0.98 | 6.14 | 5.16 |
| rs1749715 | 15:30.3 | SCD | 11:42.1 | 0.92 | 6.07 | 5.15 |
| rs1957538 | 15:21.2 | CREM | 10:35.5 | 0.05 | 5.02 | 4.97 |
| rs753151 | 08:48.7 | LIF | 22:29.0 | 0.77 | 5.53 | 4.76 |
| rs1499511 | 11:36.0 | RASA1 | 06:26.7 | 0.55 | 5.29 | 4.74 |
| rs1264898 | 02:51.8 | SNX5 | 20:17.9 | 0.20 | 4.82 | 4.62 |
| rs1503230 | 03:08.0 | LRAP | 06:36.3 | 0.22 | 4.67 | 4.45 |
| rs1417594 | 15:34.4 | VPS16 | 20:02.8 | 0.33 | 4.75 | 4.42 |
| rs1858799 | 16:23.0 | ZNF277 | 08:51.7 | 0.75 | 5.16 | 4.41 |
| rs1005989 | 03:08.9 | DGUOK | 03:14.0 | 6.40 | 1.04 | -5.36 |
| rs1986778 | 12:26.9 | TNFAIP8 | 06:58.7 | 6.02 | 0.74 | -5.28 |
| rs1862802 | 16:57.0 | TLR1 | 04:38.5 | 5.51 | 0.26 | -5.26 |
| rs1333798 | 14:27.5 | RECQL4 | 10:25.7 | 6.10 | 1.06 | -5.03 |
| rs954779 | 09:36.4 | CDC25C | 07:17.7 | 5.23 | 0.22 | -5.00 |
| rs1341446 | 04:59.6 | PIK3C3 | 18:37.9 | 7.61 | 2.71 | -4.89 |
| rs1935886 | 03:29.8 | CHI3L2 | 02:51.6 | 11.64 | 6.78 | -4.86 |
| rs1432285 | 04:14.0 | HNRPR | 01:23.5 | 5.56 | 0.74 | -4.82 |
| rs1459359 | 15:27.7 | C3orf4 | 04:39.7 | 5.10 | 0.28 | -4.82 |
| rs744531 | 03:51.7 | SLC25A32 | 09:44.5 | 5.78 | 1.00 | -4.78 |
aThe 10 top SNPs and traits for which there is evidence for linkage when age is either included or excluded as a covariate are shown as examples.