Table 1.

Suggestive linkage regions detected by RP model

Marker name (DECODE)	NPL p-value	Overall RP asymptotic p-value	Overall RP empirical p-value	Splitting covariates	Subgroup with largest likelihood ratio	λ1 and λ2 for this subgroup
H35a (102.02 cM)	0.62	0.0073	0.045	HLA-DRB1	Both without *04 allele in HLA-DRB1	0.82, 0.35
H19a (109.04 cM)	0.16	0.0014	0.016	HLA-DRB1	Both without *04 allele in HLA-DRB1	0.83, 0.40
F19b (113.69 cM)	0.23	0.0049	0.036	HLA-DRB1	Both without *04 allele in HLA-DRB1	0.84, 0.44
H8c (125.51 cM)	0.13	0.0040	0.035	HLA-DRB1	At least one has *04 allele in HLA-DRB1	1.14, 1.50
F27b (239.66 cM)	0.05	0.0006	0.009	Age at onset	Both age at onset less than median	1.34, 2.23