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. 2007 Dec 18;1(Suppl 1):S33. doi: 10.1186/1753-6561-1-s1-s33

Table 3.

Single-SNP case-control analysis for SNPs in 14 candidate genes

		Minor Allele Frequencies			p-values^a

		Cases		Controls
Gene	dbSNP ID	Affected Sibling^b(n = 816)	One Sibling per Family^c(n = 461)	(n = 855)	Affected Sibling^b	One Sibling per Family^c

PTPN22	Rs2476601	0.163	0.156	0.084	2.13 × 10^-10	4.96 × 10^-8
CTLA4	Rs3087243	0.447	0.407	0.447	0.01016	0.04618
HAVCR1	Rs6149307	0.17	0.174	0.142	0.03939	0.03193
HAVCR1	5509_5511 delCAA	0.195	0.200	0.235	0.01834	0.05172
SUMO4	Rs237025	0.517	0.520	0.456	0.00154	0.00202
SUMO4	Rs577001	0.391	0.387	0.350	0.02512	0.06162

^ap-Values were not adjusted for the multiple testing. Only significant results are presented in the table.

^bAllele frequencies and p-values were obtained using all cases and unrelated controls.

^cAllele frequencies and p-values were obtained using one randomly selected case per family and unrelated controls.