Table 1.
Power estimate of ITbp and CaMML
| Variables | Disease locus | R2 with disease locus | ITbp 100 replicates | ITbp Replicate 1–50 | CaMML Replicate 1–50 |
| DR genotypea | NA | NA | 100% | 100% | 100% |
| Sex | NA | NA | 100% | 100% | 100% |
| Smoking | NA | NA | 96% | 96% | 96% |
| chr 6_154 | C | 0.958 | 100% | 100% | 100% |
| chr 6_153 | C | 0.563 | 100% | 100% | 100% |
| chr 6_152 | C | 0.418 | 100% | 100% | 100% |
| chr 6_155 | C | 0.104 | 97% | 98% | 98% |
| chr 6_150 | C | 0.027 | 13% | 8% | 4% |
| chr 6_149 | C | 0.014 | 6% | 8% | 4% |
| chr 6_139 | C | 0.009 | 18% | 20% | 10% |
| chr 6_138 | C | 0.009 | 17% | 18% | 10% |
| chr 6_140 | C | 0.007 | 1% | 2% | 2% |
| chr 6_134 | C | 0.007 | 4% | 4% | 4% |
| chr 6_137 | C | 0.006 | 2% | 2% | 2% |
| chr 6_130 | C | 0.006 | 8% | 6% | 2% |
| chr 6_148 | C | 0.005 | 9% | 8% | 4% |
| chr 6_147 | C | 0.004 | 9% | 10% | 8% |
| chr 6_135 | C | 0.002 | 3% | 6% | 2% |
| chr 6_145 | C | 0.001 | 35% | 32% | 24% |
| chr 6_132 | C | 0.0 | 7% | 6% | 6% |
| chr 6_162 | D | 0.902 | 100% | 100% | 100% |
| chr 6_160 | D | 0.273 | 67% | 68% | 66% |
| chr 6_156 | D | 0.001 | 11% | 14% | 2% |
| chr 11_387 | F | 0.135 | 5% | 6% | 6% |
| chr 11_388 | F | 0.064 | 5% | 4% | 4% |
| chr 11_389 | F | 0.934 | 98% | 100% | 100% |
| chr 11_391 | F | 0.031 | 1% | 2% | 2% |
| chr 16_29 | A | 0.001 | 1% | 0% | 0% |
| chr 18_269 | E | 0.171 | 51% | 48% | 10% |
| chr 8_442 | B | 0.001 | 0% | 0% | 0% |
| chr 9_186 | G | 0.021 | 0% | 0% | 0% |
| chr 9_189 | H | 0.014 | 0% | 0% | 0% |
aSurrogates and covariates are in bold.