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Effects of DE-71 on liver weight of mice were treated for either 3 (A) or 34 (B,C) days with DE-71 alone or with E2 and DE-71. Controls for the 34-day time point were treated po with vehicle. Values shown are mean ± SE (n = 5–10 mice per sc group; n = 4–5 mice per po group).
*p < 0.05, **p < 0.01, and #p < 0.001 vs. vehicle. ##p < 0.05 vs. DE-71 at the same dose without EB.
