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. 2008 Feb 16;36(7):2182–2195. doi: 10.1093/nar/gkm1152

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© 2008 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Mus81-Mms4 incision on intact Holliday junctions is not enhanced by metal ion cofactor concentration. (A) Four-way junction incision as a function of Mg²⁺ and Mn²⁺ concentration. Reactions were performed with 50 nM substrate and 5 nM heterodimer, 30 min at 30°C. (B) Quantitation of assays in A. (C) Magnification of XO12 and X12 response to metal ion concentration.