Table 2.
Detection of singletons and doubletons on 385K-aCGH
SD multiplier | Singleton sensitivity | Doubleton sensitivity | FPR | Number of probes (percent of total) |
---|---|---|---|---|
0.25 | 0.869 | 0.881 | 0.993 | 251 166 (74.6) |
0.50 | 0.742 | 0.782 | 0.992 | 176 851 (52.6) |
0.75 | 0.631 | 0.698 | 0.989 | 118 501 (35.2) |
1.00 | 0.553 | 0.631 | 0.985 | 77 423 (23) |
1.25 | 0.487 | 0.560 | 0.979 | 50 327 (15) |
1.50 | 0.431 | 0.496 | 0.971 | 33 049 (9.8) |
1.75 | 0.376 | 0.425 | 0.963 | 22 172 (6.6) |
2.00 | 0.336 | 0.381 | 0.953 | 15 630 (4.6) |
2.25 | 0.300 | 0.329 | 0.942 | 11 409 (3.4) |
2.50 | 0.259 | 0.298 | 0.933 | 8594 (2.6) |
2.75 | 0.234 | 0.282 | 0.923 | 6698 (2) |
3.00 | 0.206 | 0.214 | 0.916 | 5270 (1.6) |
3.25 | 0.177 | 0.183 | 0.910 | 4226 (1.3) |
3.50 | 0.152 | 0.159 | 0.905 | 3384 (1) |
3.75 | 0.127 | 0.139 | 0.902 | 2718 (0.8) |
4.00 | 0.108 | 0.115 | 0.896 | 2200 (0.7) |
4.25 | 0.090 | 0.091 | 0.894 | 1786 (0.5) |
4.50 | 0.074 | 0.079 | 0.888 | 1415 (0.4) |
4.75 | 0.064 | 0.052 | 0.885 | 1109 (0.3) |
5.00 | 0.048 | 0.040 | 0.891 | 906 (0.3) |
5.25 | 0.037 | 0.036 | 0.897 | 735 (0.2) |
5.50 | 0.031 | 0.016 | 0.898 | 598 (0.2) |
5.75 | 0.024 | 0.012 | 0.899 | 467 (0.1) |
6.00 | 0.020 | 0.008 | 0.903 | 393 (0.1) |