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. 2008 Feb 26;36(7):2406–2417. doi: 10.1093/nar/gkn043

Figure 4.

Figure 4.

Sensitivity and PPV of structure (a) and alignment (b) prediction as a function of the weight parameter κ. The prediction accuracy is averaged over a training data set of 1000 tRNA pairs from the Sprinzl Database (32) and 1000 5S rRNA pairs from 5S Ribosomal RNA Database (27). κ = 0.45 maximizes structure prediction sensitivity. Structure prediction PPV increases asymptotically with increasing κ. Alignment prediction sensitivity and PPV both decrease slowly for κ > 1.0.