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(A) Schematic representation of the complex of let-7 miRNA with 3′-UTR of the lin-41 mRNA (LCS 2). The residues colored in green and blue match the sequences used in the monomolecular and dimeric constructs. (B) The 33-nt monomolecular RNA construct mimicking the complex. (C) The dimeric RNA construct. Numbering used in (B) has been preserved to facilitate the comparison between the two constructs. The residues originating from the lin-41 mRNA sequence are labeled by asterisk.
