. Author manuscript; available in PMC: 2008 May 6.

Published in final edited form as: J Assoc Nurses AIDS Care. 2008;19(2):158–165. doi: 10.1016/j.jana.2007.08.003

Table 1.

Patient Characteristics

Patient	Age (year/sex)	Antiretrovira Medications^*	CD4 count at start of DOT (cells/m³)	HIV concentration (viral load) at start of DOT (RNA copies/ml)	HIV concentration (viral load) at end of DOT (RNA copies/ml)	Length of time on Regimen at start of DOT	Adherence Monitoring	Number of NRTI/PI Mutations
1	15/F	AZT/3TC/TDF/SQV/LPV/r	183 (11%)	80,700 (4.91 log)	25, 900 (4.41 log)	24 weeks	Interview, MEMS, Drug levels, Pill count	5/9
2	14/F	AZT/3TC/LPV/r	119 (11%)	43,800 (4.64 log)	25, 900 (4.41 log)	126 weeks	Interview	4/3
3	19/F	TDF/DDI/EFV/LPV/r	400 (29%)	17, 200 (4.23 log)	46,700 (4.67 log)	144 weeks	Interview	6/9
4	17/M	AZT/3TC/ABC/TDF/SQV/LPV/r	50 (6%)	41,600 (4.62 log)	11,000 (4.04 log)	24 weeks	Interview, MEMS, Drug levels, Pill count	9/10
5	18/M	AZT/3TC/ABC/TDF/APV/ATV/RTV	5 (1%)	2,400,000 (6.38 log)	8,390 (3.92 log)	10 weeks	Interview Pill count	8/10

Major NRTI mutations:41L,44D, 67N, 215Y, 219Q, 184V, 215F, 69D, 70R, 74I, 75M, 118I, 210W, 184I, 210Y, 219R

Major PI mutations: 10I, 20R, 32I, 33F, 47V, 54V, 71V, 82A, 90M, 10F, 84V, 46I, 73S, 54L,63P, 82T

Antiretroviral Medications: ABC = Abacavir APV = Amprenavir ATV = Atazanavir AZT = Zidovudine 3TC = Lamivudine TDF = Tenofovir SQV = Saquinavir LPV/r = Lopinavir/ritonavir DDI = Didanosine EFV=Efavirenz