Table 1.

Status of gene evaluations in the author’s laboratory

Evaluations successfully identifying a correlating phenotype		Evaluations not successful in identifying a correlating phenotype
Gene	Correlating Phenotype(s)	Gene	Number of patients evaluated
Rhodopsin	Dominant RP (45), recessive RP (46), dominant stationary night blindness (47)	Arrestin	272 unrelated patients evaluated [Oguchi disease by another group (34)]
Rod transducin, α subunit	Dominant stationary night blindness (48)	Rod cGMP-phosphodiesterase, γ subunit	Over 1,000 unrelated patients evaluated, of whom 704 have been reported (52)
Rod cGMP-phosphodiesterase, α subunit	Recessive RP (24)	Recoverin	Evaluation of 596 unrelated patients (53)
Rod cGMP-phosphodiesterase, β subunit	Recessive RP (49)	11-cis-retinal dehydrogenase	Evaluation of 180 patients
Rhodopsin kinase	Oguchi disease (35)	Guanylate cyclase activating protein	Still actively being evaluated in the author’s laboratory
Peripherin/rds	Dominant RP (23), digenic RP (33), retinitis punctata albescens (50) [dominant retinitis pigmentosa and dominant macular dystrophies and cone/rod degenerations by other groups (22,51)]	IRBP (interphotoreceptor retinoid binding protein)	Still actively being evaluated in the author’s laboratory
ROM1	Digenic RP (33)	TULP1 (tubby-like protein-1) (54)	Still actively being evaluated in the author’s laboratory