Table 2.

Relation of RER phenotype with single genetic alterations in the first series of tumors

Measurement	Criterion	Tumors, n		χ2 P
		RER+	RER−
DNA index	n < 1.3	13	29	<10−4
	n ≥ 1.3	0	46
LOH
17p	Yes	0	50	<10−4
	No	13	21
5q	Yes	0	44	2 × 10−3
	No	9	24
Mutation
p53	Yes	4	41	NS
	No	9	33
K-ras	Yes	2	24	NS
	No	7	39
APC	Yes	1	53	2 × 10−4
	No	8	15
TGF-βRII	Yes	13	1	<10−4
	No	0	74

LOH, loss of heterozygosity; NS, not significant.