Table 1.
Incidence of hyperbilirubinemia as a function of presence of the G-6-PD Mediterranean mutation and the UDPGT1 genotype
G-6-PD Mediterranean | Incidence of UDPGT1 genotype
|
|||
---|---|---|---|---|
6/6 | 6/7 | 7/7 | Total | |
Present (deficient) | 6/62 (9.7%) | 18/57 (31.6%) | 6/12 (50%) | 30/131 (22.9%) |
Absent (normal) | 10/101 (9.9%) | 7/105 (6.7%) | 5/34 (14.7%) | 22/240 (9.2%) |
Significance | NS | P < 0.0001 | P = 0.02 | P = 0.0005 |
6/6, Homozygous normal UDPGT1 genotype; 6/7, heterozygous variant UDPGT1 genotype; 7/7, homozygous UDPGT1 genotype.