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Fold-increase (FI) in expression of genes involved in lipid metabolism in the livers of ACE−/− mice compared with ACE+/+ mice
| Gene | FI | Role in fat metabolism |
|---|---|---|
| Lipoprotein lipase | 4.4* | Lipolysis |
| PPARγ coactivator-1 | 2.8* | Induction of fat metabolism |
| Carnitine palmitoyl transferase | 2.3* | Fatty acid oxidation |
| Long chain acyl-CoA dehydrogenase | 2.1* | Fatty acid oxidation |
| Hormone sensitive lipase | 1.4 | Lipolysis |
| Fatty acid synthase | 1.0 | Fat storage |
*, P < 0.05 (ACE−/− vs. ACE+/+).
