Fig. 2.

Abnormal hair growth from grafted Cdsn-deficient mouse skin. Embryonic skin obtained from the trunks of wild-type mice (uppermost row), heterozygous Cdsn-deficient mice (second row from top), and homozygous Cdsn-deficient mice (third row from top) was grafted onto the backs of nude mice. Gross appearance of the grafted skins 2 weeks (Left) and 4 weeks (Right) after transplantation. Thin and slightly curly hairs from skin of homozygous Cdsn-deficient mice at 2 and 4 weeks after transplantation are shown from different angles bottom most row. Representative results of one mouse for each group examined (wild-type, n = 2; heterozygous Cdsn-deficient, n = 4; homozygous Cdsn-deficient, n = 3) are shown.