Fig. 13.

Performance of the accessible surface potential as a function of its burial range and the size of the known structures used to calculate the potential. Four sets of known protein structures were used to extract the potentials: small (<100 residues; ○), medium (100–200 residues; •), large (>200 residues; □), and all (the sma-med-large set; broken line) (Materials and Methods). Model assessment by these potentials was evaluated separately for the four 100/100 very small (A), small (B), medium size (C), and large model test sets (D), as well as for the combined 400/400 test set (E) (Materials and Methods). The potentials were calculated as specified in Table 2.