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. 2002 May;11(5):1050–1061. doi: 10.1110/ps.2270102

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2002, © Oxford University Press

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Fig. 7. — Graphical Representation and Analysis of Structural Properties (GRASP) representation of the nFGF-1-SOS complex. SOS (indicated in yellow) could be observed to be lodged in the putative heparin-binding site (shown in blue). The negatively charged ligand (SOS) appears to stabilize the (nFGF-1) molecule (indicated in green) through electrostatic interactions with the closely spaced positively charged residues in the heparin-binding site. Binding of SOS appears to decrease the repulsion force(s) operating in the "cationic cluster."