TABLE 1.
PERCENT RECOVERY OF PPS IN URINE AFTER INTRAVENOUS ADMINISTRATION IN RABBITS
| Unfractionated PPS (median total recovery 47.2%) | ||||
|---|---|---|---|---|
| Rabbit | 1st 24 hours | 2nd 24 hours | 3rd 24 hours | Total recovery |
| 1 | 19.3 | 2.6 | 0 | 21.9 |
| 2 | 29.2 | 4.8 | 0 | 34.0 |
| 3 | 52.6 | 3.5 | 4.4 | 60.5 |
| 4 | 5.7 | 12.0 | 2.0 | 19.7 |
| 5 | 67.9 | 5.3 | 0 | 73.2 |
| 6 | 60.2 | 5.8 | 0 | 66.0 |
| Low molecular weight PPS (median total recovery 74.6%) | ||||
| Rabbit | 1st 24 hours | 2nd 24 hours | 3rd 24 hours | Total recovery |
| 1 | 76.7 | 8.4 | 2.3 | 87.4 |
| 2 | 89.6 | 2.9 | 3.8 | 96.3 |
| 3 | 85.9 | 3.2 | 0 | 89.1 |
| 4 | 61.7 | No urine | No urine | 61.7 |
| 5 | 48.0 | 12.3 | 0 | 60.3 |
| 6 | 22.0 | 9.4 | 0 | 31.4 |
| High molecular weight PPS (median total recovery 3.3%) | ||||
| Rabbit | 1st 24 hours | 2nd 24 hours | 3rd 24 hours | Total recovery |
| 1 | 1.5 | 1.4 | 0 | 2.9 |
| 2 | 2.2 | 1.4 | 0 | 3.2 |
| 3 | 2.6 | 2.4 | 0 | 5.0 |
| 4 | 2.6 | 0.8 | 0 | 3.4 |
| 5 | 3.0 | 1.9 | 0 | 4.9 |
| 6 | 1.0 | 1.5 | 0 | 2.5 |