Table 2.

Enantiomeric ratio, E, and its thermodynamic components for the kinetic resolution of some sec-alcohols catalyzed by Candida antqrctica lipase B

sec-alcohol	E (298 K)	ΔR-SΔG‡ (298 K) (kJ/mol)	ΔR-SΔH‡ (kJ/mol)	TΔR-SΔS‡ (298 K) (kJ/mol)	ΔR-SΔS‡ (J/mol, K)	TR (K)
1-bromo-2-butanol	100	−11.4	−23.5 ± 1.0	−12.1 ± 1.0	−40.7 ± 3.2	580
3-hexanol	340	−14.4	−9.0 ± 0.7	+5.5 ± 0.7	+18.3 ± 2.4	−490
2-butanola	8.3	−5.26	−10.7 ± 1.4	−5.4 ± 1.4	−18.2 ± 4.6	590
3-methyl-2-butanolb	810	−16.6	−24.3 ± 1.1	−7.7 ± 1.0	−26.0 ± 3.4	940
3,3-dimethyl-2-butanola	460	−15.2	−20.4 ± 1.3	−5.2 ± 1.3	−17.6 ± 4.2	1160

E at 298 K was calculated from the linear relation between lnE and T⁻¹. Standard errors given were calculated from the linear regression.

^a Data from Overbeeke et al. 1999.

^b Data partly from Overbeeke et al. 1999.