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. 2008 May 12;205(5):1099–1108. doi: 10.1084/jem.20070850

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© 2008 Smith-Bouvier et al.

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Figure 6. — Effect of sex chromosome complement on IL-13Rα2 expression. Freshly isolated splenocytes from PLP 139–151 immunized SJL mice of the XX or the XY⁻ sex chromosome complement were analyzed for the expression of IL-13Rα2 (top) and IL-13Rα1 (bottom) on B cells (CD19⁺), macrophages (CD11b⁺), dendritic cells (CD11c⁺), and myeloid dendritic cells (CD11c⁺CD11b⁺) by flow cytometry. XX, thick red lines; XY⁻, blue lines; shaded area, negative control. The mean fluorescent intensities are indicated on FACS plots (red, XX; blue, XY⁻). IL-13Rα2 expression was significantly higher on macrophages, dendritic cells, and myeloid dendritic cells in XX mice than in XY⁻ mice. *, P < 0.05; n = 3 each. Results represent two independent experiments.