Table II.
Clinical features of adoptive EAE in WT female SJL mice that received PLP 139-151 reactive LN cells from either XX ovariectomized female SJL mice or XY− ovariectomized female SJL mice
| Genotype of donor cells | Incidence | Mortality | Mean day of onset | Mean peak | Mean score (all days) |
|---|---|---|---|---|---|
| Experiment 1 | |||||
| XX females | 12/12 | 7/12 | 9.4 | 4.6a | 3.5a |
| XY− females | 2/11 | 0/11 | 10.5 | 3.3 | 0.2 |
| Experiment 2b | |||||
| XX females | 13/13 | 2/13 | 9.9 | 4.0a | 2.7a |
| XY− females | 5/8 | 1/8 | 11.2 | 3.6 | 1.1 |
a
A significant difference between groups; P < 0.05.
b
These data are depicted in Fig. 2.