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. Author manuscript; available in PMC: 2009 Apr 15.
Published in final edited form as: Biochem Pharmacol. 2008 Feb 2;75(8):1588–1600. doi: 10.1016/j.bcp.2008.01.007

Table 2.

MIC results with selected nucleosides

Compound Name specific activity (nmol/mg-min) H37Ra SRICK1 SRICK1::adoK
MICa(μg/ml)
5′-amino-5′-deoxy-Ado NDb >100 >100 >100
9-[β-D-5-methyl-(allo)-ribofuranosyl]-2-fluoro-adenine 4 1–10 >50 0.1–1
9-[α-L-lyxofuranosyl]-2-fluoro-adenine 130 10–100 >100 10–100
a

MIC assays were performed at least twice for each compound.

b

ND specific activity was not determined for this compound.