Fig. 5.
Summary of the short- and medium-range backbone amide proton NOEs, semiquantitative JHNHα coupling constant analysis, proton/deuteron exchange protection patterns, and chemical shift index (CSI) information. (lines capped with filled circles) NOE correlation between the given residues; (open circles and filled squares) JHNHα coupling constant values of <6 and >9 Hz, respectively; (filled circles) amide protons that were protected after 24 hours in the proton/deuteron exchange protection experiments. Helical regions are indicated by −1 and +1 values in the 1H CSI and 13C CSI analysis, respectively. Opposite values are indicative of an extended backbone conformation. CSI analysis was performed according to Wishart and Sykes (1994).