Table 1.

The interactions of β-lactams with PBP 5 as judged by ΔT_m, ΔΔG_u, and k₂/K′ values

^a Determined by the method of Schellman (Becktel and Schellman 1987): ΔΔG_u = ΔT_m • ΔS_apo-enzyme.

^b Determined by direct comparison of the equilibria within the unfolding region, namely at T = 51.3°C, using the Gibbs-Helmholtz equation.