Table 3.
NTP | M. tuberculosis | E. coli |
ATP | 100 | 100 |
dATP | 120 | 76 |
ITP | 66 | 1 |
GTP | 60 | 15 |
CTP | 42 | 24 |
UTP | 26 | 13 |
The reaction medium (0.5 mL final volume) was the same as described in Table 2. The concentrations of dTMP and nucleoside triphosphate were kept constant at 0.5 mM for TMPKmt and at 0.3 mM and 1 mM respectively for TMPKec. Activities with various NTPs are given considering the reaction rate with ATP as 100%.