Table 2.
Calculated partition coefficients quantifying the extent of accumulation of urea and GuHCl near different types of protein surface
| Type | KP,urea | KP,GuHCl |
| Polar peptide backbone | 2.0 ± 0.1 | 2.3 ± 0.2 |
| Charged groups | 1.0a ± 0.1 | 1.5 ± 0.4 |
| Other polar, nonpolar | 1.0a ± 0.1 | 1.0 ± 0.1 |
a Fit together.