Table 2.

Calculated and observed hydrodynamic radii of α-synuclein in the presence and absence of 1 M perdeuterated glucose at pH 7 and 298 K

	Calculated for a 140 residue globular protein		Observeda
	Native	Highly denatured	Dilute	1 M glucose
RH (Å)	17.8–19.9	33.3–36.9	26.6 ± 0.5	22.5 ± 0.6

^a The uncertainties are from linear least-squares fitting of Equation 3 and propagation of the uncertainties through Equation 4.